Affiliation:
1. School of Electronic and Information Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China
2. Key Laboratory of Media Convergence Technology and Communication, Lanzhou 730070, China
Abstract
In order to investigate the impact of two immunization strategies—vaccination targeting susceptible individuals to reduce their infection rate and clinical medical interventions targeting infected individuals to enhance their recovery rate—on the spread of infectious diseases in complex networks, this study proposes a bilinear SIR infectious disease model that considers bidirectional immunization. By analyzing the conditions for the existence of endemic equilibrium points, we derive the basic reproduction numbers and outbreak thresholds for both homogeneous and heterogeneous networks. The epidemic model is then reconstructed and extensively analyzed using continuous-time Markov chain (CTMC) methods. This analysis includes the investigation of transition probabilities, transition rate matrices, steady-state distributions, and the transition probability matrix based on the embedded chain. In numerical simulations, a notable concordance exists between the outcomes of CTMC and mean-field (MF) simulations, thereby substantiating the efficacy of the CTMC model. Moreover, the CTMC-based model adeptly captures the inherent stochastic fluctuation in the disease transmission, which is consistent with the mathematical properties of Markov chains. We further analyze the relationship between the system’s steady-state infection density and the immunization rate through MCS. The results suggest that the infection density decreases with an increase in the immunization rate among susceptible individuals. The current research results will enhance our understanding of infectious disease transmission patterns in real-world scenarios, providing valuable theoretical insights for the development of epidemic prevention and control strategies.
Funder
National Natural Science Foundation of China
Science and Technology Project of Education Department of Gansu Province
Gansu Provincial Science and Technology Plan Project, China
Special Funds for Guiding Local Scientific and Technological Development by the Central Government
Natural Science Foundation of Gansu Province, China
Support Project for Youth Doctor in Colleges and Universities of Gansu Province
Cited by
1 articles.
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