The Aerogen® Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin

Author:

Dallas Ronald H.,Rains Jason K.,Wilder Keith,Humphrey William,Cross Shane J.ORCID,Ghafoor Saad,Brazelton de Cardenas Jessica N.,Hayden Randall T.,Hijano Diego R.ORCID

Abstract

Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it is difficult to set up and maintain. We developed a method for delivery of this medication using the vibrating mesh nebulizer (Aerogen®). We did not observe any adverse events with this method.

Publisher

MDPI AG

Subject

Pharmaceutical Science

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