Physiologically Based Pharmacokinetic Modeling in Pregnancy, during Lactation and in Neonates: Achievements, Challenges and Future Directions-Reference-Cited by-同舟云学术

Physiologically Based Pharmacokinetic Modeling in Pregnancy, during Lactation and in Neonates: Achievements, Challenges and Future Directions

Published:2024-04-05 Issue:4 Volume:16 Page:500
ISSN:1999-4923
Container-title:Pharmaceutics
language:en
Short-container-title:Pharmaceutics

Author:

Allegaert Karel¹²³^ORCID,Quinney Sara K.⁴,Dallmann André⁵^ORCID

Affiliation:

1. Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium

2. Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium

3. Department of Hospital Pharmacy, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands

4. Department of OB/GYN, Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub, Indiana University School of Medicine, Indianapolis, IN 46202, USA

5. Bayer HealthCare SAS, Loos, France, on Behalf of Bayer AG, Pharmacometrics/Modeling and Simulation, Systems Pharmacology & Medicine–PBPK, 51368 Leverkusen, Germany

Abstract

Obstetric subjects represent a special population in pharmacology [...]

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

MDPI AG

Link

https://www.mdpi.com/1999-4923/16/4/500/pdf

Reference17 articles.

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3. Assuring access to safe medicines in pregnancy and breastfeeding;Nooney;Clin. Pharmacol. Ther.,2021

4. Physiologic changes during pregnancy and impact on small-molecule drugs, biological (monoclonal antibody) disposition, and response;Eke;J. Clin. Pharmacol.,2023

5. Clinical pharmacokinetic studies in pregnant women and the relevance of pharmacometrics tools;Dallmann;Curr. Pharm. Des.,2019