Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems

Author:

Paramshetti Sharanya1ORCID,Angolkar Mohit1ORCID,Al Fatease Adel2ORCID,Alshahrani Sultan M.34ORCID,Hani Umme2ORCID,Garg Ankitha1,Ravi Gundawar5ORCID,Osmani Riyaz Ali M.1ORCID

Affiliation:

1. Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research (JSSAHER), Mysuru 570015, India

2. Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia

3. Clinical Pharmacy Department, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia

4. College of Applied Medical Sciences, Bisha University, Bisha 67714, Saudi Arabia

5. Department of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, India

Abstract

The first conductive polymers (CPs) were developed during the 1970s as a unique class of organic substances with properties that are electrically and optically comparable to those of inorganic semiconductors and metals while also exhibiting the desirable traits of conventional polymers. CPs have become a subject of intensive research due to their exceptional qualities, such as high mechanical and optical properties, tunable electrical characteristics, ease of synthesis and fabrication, and higher environmental stability than traditional inorganic materials. Although conducting polymers have several limitations in their pure state, coupling with other materials helps overcome these drawbacks. Owing to the fact that various types of tissues are responsive to stimuli and electrical fields has made these smart biomaterials attractive for a range of medical and biological applications. For various applications, including the delivery of drugs, biosensors, biomedical implants, and tissue engineering, electrical CPs and composites have attracted significant interest in both research and industry. These bimodalities can be programmed to respond to both internal and external stimuli. Additionally, these smart biomaterials have the ability to deliver drugs in various concentrations and at an extensive range. This review briefly discusses the commonly used CPs, composites, and their synthesis processes. Further highlights the importance of these materials in drug delivery along with their applicability in various delivery systems.

Funder

Deanship of Scientific Research at King Khalid University

Publisher

MDPI AG

Subject

Pharmaceutical Science

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