Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems

Author:

Shukla Monu Kumar1ORCID,Tiwari Harshita2,Verma Rachna3ORCID,Dong Wen-Liang4,Azizov Shavkatjon56ORCID,Kumar Brajesh7ORCID,Pandey Sadanand8ORCID,Kumar Deepak1ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, India

2. Discovery Informatics Lab, Natural Products & Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu 180001, India

3. Department of Basic Sciences, Shoolini University, Solan 173229, India

4. School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China

5. Laboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Academy of Sciences Uzbekistan, Tashkent 100125, Uzbekistan

6. Department of Pharmaceutical Chemistry, Tashkent Pharmaceutical Institute, Tashkent 100015, Uzbekistan

7. Department of Chemistry, TATA College, Kolhan University, Chaibasa 833202, India

8. Department of Chemistry, College of Natural Sciences, Yeungnam University, Gyeongsan 38541, Republic of Korea

Abstract

Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids “Solutions for Your Success” have received a lot of interest from scientists due to a myriad of applications in the pharmaceutical industry for drug delivery systems as well as targeting different diseases. Solubility is a critical physicochemical property that determines the drug’s fate at the target site. Many promising drug candidates fail in various phases of drug research due to poor solubility. In this context, ionic liquids are regarded as effective drug delivery systems for poorly soluble medicines. ILs are also able to combine different anions/cations with other cations/anions to produce salts that satisfy the concept behind the ILs. The important characteristics of ionic liquids are the modularity of their physicochemical properties depending on the application. The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields.

Publisher

MDPI AG

Subject

Pharmaceutical Science

Reference98 articles.

1. Introduction: Ionic liquids;Lei;Chem. Rev.,2017

2. Green solvents for the formation of amide linkages;Procopio;Org. Biomol. Chem.,2022

3. Molecular weights and electrical conductivity of several fused salts;Walden;Bull. Acad. Imper. Sci.,1914

4. Air and water stable 1-ethyl-3-methylimidazolium based ionic liquids;Wilkes;J. Chem. Soc. Chem. Commun.,1992

5. Mild and efficient one-pot synthesis of (E)-styrylperfluoroalkyl ketone from styrene;Rao;Results Chem.,2022

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