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Dose Optimization and Targeting Strategies of Anti-Infective Agents

  • Published:2023-07-03 Issue:7 Volume:15 Page:1870
  • ISSN:1999-4923
  • Container-title:Pharmaceutics
  • language:en
  • Short-container-title:Pharmaceutics

Author:

Šíma Martin1ORCID,Slanař Ondřej1ORCID

Affiliation:

1. Department of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 00 Prague, Czech Republic

Abstract

Most drugs are currently developed, approved and marketed based on their effect on the majority of the population [...]

Funder

Charles University

Publisher

MDPI AG

Subject

Pharmaceutical Science

Reference7 articles.

1. Huntjens, D.W., Dijkstra, J.A., Verwiel, L.N., Slijkhuis, M., Elbers, P., Welkers, M.R.A., Veldkamp, A.I., Kuijvenhoven, M.A., de Leeuw, D.C., and Abdullah-Koolmees, H. (2023). Optimizing Antiviral Dosing for HSV and CMV Treatment in Immunocompromised Patients. Pharmaceutics, 15.

2. Katip, W., Oberdorfer, P., and Kasatpibal, N. (2022). Effectiveness and Nephrotoxicity of Loading Dose Colistin-Meropenem versus Loading Dose Colistin-Imipenem in the Treatment of Carbapenem-Resistant Acinetobacter baumannii Infection. Pharmaceutics, 14.

3. Sima, M., Bobek, D., Cihlarova, P., Rysanek, P., Rousarova, J., Berousek, J., Kuchar, M., Vymazal, T., and Slanar, O. (2022). Factors Affecting the Metabolic Conversion of Ciprofloxacin and Exposure to Its Main Active Metabolites in Critically Ill Patients: Population Pharmacokinetic Analysis of Desethylene Ciprofloxacin. Pharmaceutics, 14.

4. Zhang, J., Wu, M., Diao, S., Zhu, S., Song, C., Yue, J., Martins, F.S., Zhu, P., Lv, Z., and Zhu, Y. (2023). Pharmacokinetic/Pharmacodynamic Evaluation of Aztreonam/Amoxicillin/Clavulanate Combination against New Delhi Metallo-beta-Lactamase and Serine-beta-Lactamase Co-Producing Escherichia coli and Klebsiella pneumoniae. Pharmaceutics, 15.

5. Hartinger, J.M., Michalickova, D., Dvorackova, E., Hronova, K., Krekels, E.H.J., Szonowska, B., Bednarova, V., Benakova, H., Kroneislova, G., and Zavora, J. (2023). Intraperitoneally Administered Vancomycin in Patients with Peritoneal Dialysis-Associated Peritonitis: Population Pharmacokinetics and Dosing Implications. Pharmaceutics, 15.
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