Abstract
Single-antenna microwave ablation (MWA) is mainly used to treat small tumors less than 3 cm in diameter. To obtain a larger coagulation zone in a single ablation, a dual-antenna ablation approach was proposed. A three-dimensional finite element method (FEM) simulation model of parallel dual-antennas was developed. Ex vivo experiments at 50 W for 8 min were performed to verify the model. Both the temperature changes in tissue and the size of the coagulation zone were recorded. The effects of dual-antenna spacing, heating power, and blood perfusion on the coagulation zone were analyzed. Fifteen experiments were carried out. The errors between the mean measurements and simulated results at the set temperature points were 1.08 °C, 0.95 °C, and 2.1 °C, respectively. For the same conditions, the blood perfusion of 1.0, 1.5, and 3.0 kg/(m3·s) can result in a reduction in the coagulation volume by 18.4%, 25.4%, and 42.5%. As the spacing increased, the coagulation zone of each antenna started to fuse together later and the resulting integral coagulation zone became larger. Dual-antenna MWA is expected to be used for the treatment of tumors larger than 5 cm in diameter.
Funder
National Natural Science Foundation of China
Subject
Fluid Flow and Transfer Processes,Computer Science Applications,Process Chemistry and Technology,General Engineering,Instrumentation,General Materials Science
Cited by
3 articles.
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