Kinetic Isotope Effect of Prostaglandin H Synthase Exhibits Inverted Temperature Dependence
Author:
Publisher
MDPI AG
Subject
Physical and Theoretical Chemistry,Catalysis
Link
http://www.mdpi.com/2073-4344/4/2/174/pdf
Reference45 articles.
1. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2;Smith;J. Biol. Chem.,1996
2. Prostaglandins and Thromboxanes
3. Tyrosine-385 of prostaglandin endoperoxide synthase is required for cyclooxygenase catalysis;Shimokawa;J. Biol. Chem.,1990
4. Tyrosyl radicals in prostaglandin H synthase-1 and -2
5. Structural insights into the stereochemistry of the cyclooxygenase reaction
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1. Role of water in cyclooxygenase catalysis and design of anti-inflammatory agents targeting two sites of the enzyme;Scientific Reports;2020-07-01
2. A Revised Mechanism for Human Cyclooxygenase-2;Journal of Biological Chemistry;2016-01
3. Energetics of the biosynthesis of prostanes from arachidonate;Tetrahedron;2015-09
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