Recent Advancements in Hydrogel Biomedical Research in Italy

Author:

Zanrè Eleonora12ORCID,Dalla Valle Eva12ORCID,D’Angelo Edoardo23ORCID,Sensi Francesca2,Agostini Marco23ORCID,Cimetta Elisa12ORCID

Affiliation:

1. Department of Industrial Engineering (DII), University of Padova, 35131 Padova, Italy

2. Fondazione Istituto di Ricerca Pediatrica Città della Speranza (IRP), 35127 Padova, Italy

3. General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy

Abstract

Hydrogels have emerged as versatile biomaterials with remarkable applications in biomedicine and tissue engineering. Here, we present an overview of recent and ongoing research in Italy, focusing on extracellular matrix-derived, natural, and synthetic hydrogels specifically applied to biomedicine and tissue engineering. The analyzed studies highlight the versatile nature and wide range of applicability of hydrogel-based studies. Attention is also given to the integration of hydrogels within bioreactor systems, specialized devices used in biological studies to culture cells under controlled conditions, enhancing their potential for regenerative medicine, drug discovery, and drug delivery. Despite the abundance of literature on this subject, a comprehensive overview of Italian contributions to the field of hydrogels-based biomedical research is still missing and is thus our focus for this review. Consolidating a diverse range of studies, the Italian scientific community presents a complete landscape for hydrogel use, shaping the future directions of biomaterials research. This review aspires to serve as a guide and map for Italian researchers interested in the development and use of hydrogels in biomedicine.

Funder

European Research Council

Publisher

MDPI AG

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