Electroencephalographic Effective Connectivity Analysis of the Neural Networks during Gesture and Speech Production Planning in Young Adults

Abstract

Gestures and speech, as linked communicative expressions, form an integrated system. Previous functional magnetic resonance imaging studies have suggested that neural networks for gesture and spoken word production share similar brain regions consisting of fronto-temporo-parietal brain regions. However, information flow within the neural network may dynamically change during the planning of two communicative expressions and also differ between them. To investigate dynamic information flow in the neural network during the planning of gesture and spoken word generation in this study, participants were presented with spatial images and were required to plan the generation of gestures or spoken words to represent the same spatial situations. The evoked potentials in response to spatial images were recorded to analyze the effective connectivity within the neural network. An independent component analysis of the evoked potentials indicated 12 clusters of independent components, the dipoles of which were located in the bilateral fronto-temporo-parietal brain regions and on the medial wall of the frontal and parietal lobes. Comparison of effective connectivity indicated that information flow from the right middle cingulate gyrus (MCG) to the left supplementary motor area (SMA) and from the left SMA to the left precentral area increased during gesture planning compared with that of word planning. Furthermore, information flow from the right MCG to the left superior frontal gyrus also increased during gesture planning compared with that of word planning. These results suggest that information flow to the brain regions for hand praxis is more strongly activated during gesture planning than during word planning.