Association between Shift Work and Health Outcomes in the General Population in China: A Cross-Sectional Study

Author:

Gao Nan12,Zheng Yongbo23ORCID,Yang Yingbo1,Huang Yuetong2,Wang Sanwang24,Gong Yimiao2,Zeng Na56,Ni Shuyu56,Wu Shuilin56,Su Sizhen2,Zhang Zhibo2,Yuan Kai2,Shi Le2,Zhang Zhaohui1,Yan Wei2,Lu Lin2357,Bao Yanping56

Affiliation:

1. The First Affiliated Hospital of Xinxiang Medical University, Xinxiang Medical University, Xinxiang 453199, China

2. Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University, Beijing 100191, China

3. Peking-Tsinghua Centre for Life Sciences and PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing 100191, China

4. Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan 430060, China

5. National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing 100191, China

6. School of Public Health, Peking University, Beijing 100191, China

7. Research Unit of Diagnosis and Treatment of Mood Cognitive Disorder, Chinese Academy of Medical Sciences (No. 2018RU006), Beijing 100191, China

Abstract

Shift work may adversely affect individuals’ health, thus, the current study aimed to investigate the association between shift work and health outcomes in the general population. A total of 41,061 participants were included in this online cross-sectional survey, among which 9612 (23.4%) individuals engaged in shift work and 31,449 (76.6%) individuals engaged in non-shift work. Multiple logistic regression analyses were conducted to explore the association between shift work and health outcomes (psychiatric disorders, mental health symptoms, and physical disorders). In addition, associations between the duration (≤1 year, 1–3 years, 3–5 years, 5–10 years, ≥10 years) and frequency of shift work (<1 or ≥1 night/week) and health outcomes were also explored. The results showed that compared to non-shift workers, shift workers had a higher likelihood of any psychiatric disorders (odds ratios [OR] = 1.80, 95% CI = 1.56–2.09, p < 0.001), mental health symptoms (OR = 1.76, 95% CI = 1.68–1.85, p < 0.001), and physical disorders (OR = 1.48, 95% CI = 1.39–1.57, p < 0.001). In addition, inverted U-shaped associations were observed between the duration of shift work and health outcomes. These results indicated that shift work was closely related to potential links with poor health outcomes. The findings highlighted the importance of paying attention to the health conditions of shift workers and the necessity of implementing comprehensive protective measures for shift workers to reduce the impact of shift work.

Funder

National Programs for Brain Science and Brain-like Intelligence Technology of China

National Natural Science Foundation of China

Postgraduate Edu-cation Reform and Quality Improvement Project of Henan Province

Publisher

MDPI AG

Subject

General Neuroscience

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