Sleep Deprivation and Insomnia in Adolescence: Implications for Mental Health

Author:

Uccella Sara12ORCID,Cordani Ramona12,Salfi Federico3ORCID,Gorgoni Maurizio45ORCID,Scarpelli Serena4ORCID,Gemignani Angelo6,Geoffroy Pierre Alexis78ORCID,De Gennaro Luigi45ORCID,Palagini Laura910,Ferrara Michele3ORCID,Nobili Lino12

Affiliation:

1. Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16126 Genoa, Italy

2. Child Neuropsychiatry Unit, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy

3. Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, Italy

4. Department of Psychology, Sapienza University of Rome, 00185 Rome, Italy

5. Body and Action Lab, IRCSS Fondazione Santa Lucia, 00179 Rome, Italy

6. Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Azienda Ospedaliera Universitaria Pisana AUOP, 56126 Pisa, Italy

7. Département de Psychiatrie et D’addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat—Claude Bernard, 75018 Paris, France

8. GHU Paris—Psychiatry & Neurosciences, 1 Rue Cabanis, Université de Paris, NeuroDiderot, Inserm, 75019 Paris, France

9. Psychiatric Clinic, Department of Clinical and Experimental Medicine, Azienda Ospedaliero Universitaria Pisana AUOP, 56126 Pisa, Italy

10. Institute of Psychiatry, Department of Neuroscience and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy

Abstract

Sleep changes significantly throughout the human lifespan. Physiological modifications in sleep regulation, in common with many mammals (especially in the circadian rhythms), predispose adolescents to sleep loss until early adulthood. Adolescents are one-sixth of all human beings and are at high risk for mental diseases (particularly mood disorders) and self-injury. This has been attributed to the incredible number of changes occurring in a limited time window that encompasses rapid biological and psychosocial modifications, which predispose teens to at-risk behaviors. Adolescents’ sleep patterns have been investigated as a biunivocal cause for potential damaging conditions, in which insufficient sleep may be both a cause and a consequence of mental health problems. The recent COVID-19 pandemic in particular has made a detrimental contribution to many adolescents’ mental health and sleep quality. In this review, we aim to summarize the knowledge in the field and to explore implications for adolescents’ (and future adults’) mental and physical health, as well as to outline potential strategies of prevention.

Funder

Italian Ministry of Health

Ministry of University and Research

National Recovery and Resilience Plan

project MNESYS

Publisher

MDPI AG

Subject

General Neuroscience

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