Affiliation:
1. The Beijing Municipal Key Laboratory of Multimedia and Intelligent Software Technology, Beijing Institute of Artificial Intelligence, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China
Abstract
Using machine learning methods to estimate brain effective connectivity networks from functional magnetic resonance imaging (fMRI) data has garnered significant attention in the fields of neuroinformatics and bioinformatics. However, existing methods usually require retraining the model for each subject, which ignores the knowledge shared across subjects. In this paper, we propose a novel framework for estimating effective connectivity based on an amortization transformer, named AT-EC. In detail, AT-EC first employs an amortization transformer to model the dynamics of fMRI time series and infer brain effective connectivity across different subjects, which can train an amortized model that leverages the shared knowledge from different subjects. Then, an assisted learning mechanism based on functional connectivity is designed to assist the estimation of the brain effective connectivity network. Experimental results on both simulated and real-world data demonstrate the efficacy of our method.
Funder
R&D Program of Beijing Municipal Education Commission
National Natural Science Foundation of China Research Program
Cited by
3 articles.
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