Intracerebral Hemorrhage Prognosis Classification via Joint-Attention Cross-Modal Network

Author:

Xu Manli1,Fu Xianjun2ORCID,Jin Hui3,Yu Xinlei3,Xu Gang2,Ma Zishuo4,Pan Cheng5,Liu Bo678

Affiliation:

1. The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China

2. School of Artificial Intelligence, Zhejiang College of Security Technology, Wenzhou 325016, China

3. School of Computer, Hangzhou Dianzi University, Hangzhou 310018, China

4. International Business School, Jinan University, Zhuhai 510632, China

5. School of General Education, Sanda University, Shanghai 201209, China

6. The 39th Research Institute of China Electronics Technology Group Corporation, Xi’an 710065, China

7. Key Laboratory of Antenna and Control Technology of Shanxi Province, Xi’an 710068, China

8. School of Management, Xi’an Jiaotong University, Xi’an 710049, China

Abstract

Intracerebral hemorrhage (ICH) is a critical condition characterized by a high prevalence, substantial mortality rates, and unpredictable clinical outcomes, which results in a serious threat to human health. Improving the timeliness and accuracy of prognosis assessment is crucial to minimizing mortality and long-term disability associated with ICH. Due to the complexity of ICH, the diagnosis of ICH in clinical practice heavily relies on the professional expertise and clinical experience of physicians. Traditional prognostic methods largely depend on the specialized knowledge and subjective judgment of healthcare professionals. Meanwhile, existing artificial intelligence (AI) methodologies, which predominantly utilize features derived from computed tomography (CT) scans, fall short of capturing the multifaceted nature of ICH. Although existing methods are capable of integrating clinical information and CT images for prognosis, the effectiveness of this fusion process still requires improvement. To surmount these limitations, the present study introduces a novel AI framework, termed the ICH Network (ICH-Net), which employs a joint-attention cross-modal network to synergize clinical textual data with CT imaging features. The architecture of ICH-Net consists of three integral components: the Feature Extraction Module, which processes and abstracts salient characteristics from the clinical and imaging data, the Feature Fusion Module, which amalgamates the diverse data streams, and the Classification Module, which interprets the fused features to deliver prognostic predictions. Our evaluation, conducted through a rigorous five-fold cross-validation process, demonstrates that ICH-Net achieves a commendable accuracy of up to 87.77%, outperforming other state-of-the-art methods detailed within our research. This evidence underscores the potential of ICH-Net as a formidable tool in prognosticating ICH, promising a significant advancement in clinical decision-making and patient care.

Funder

Wenzhou Science and Technology Bureau Project

Publisher

MDPI AG

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