Convergent Validity of the Timed Walking Tests with Functional Ambulatory Category in Subacute Stroke

Author:

Cinnera Alex Martino1ORCID,Marrano Serena1,De Bartolo Daniela12ORCID,Iosa Marco13ORCID,Bisirri Alessio4ORCID,Leone Enza56,Stefani Alessandro7,Koch Giacomo18,Ciancarelli Irene9,Paolucci Stefano1,Morone Giovanni910ORCID

Affiliation:

1. Santa Lucia Foundation, Scientific Institute for Research, Hospitalization and Health Care (IRCCS), 00179 Rome, Italy

2. Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences & Institute for Brain and Behaviour Amsterdam, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands

3. Department of Psychology, Sapienza University of Rome, 00185 Rome, Italy

4. Villa Sandra Institute, Via Portuense, 798, 00148 Rome, Italy

5. School of Allied Health Professions, Faculty of Medicine and Health Sciences, Keele University, Staffordshire ST5 5BG, UK

6. Centre for Biomechanics and Rehabilitation Technologies, Staffordshire University, Stoke-on-Trent ST4 2DF, UK

7. Department of System Medicine, Faculty of Medicine and Surgery, University of Rome Tor Vergata, 00133 Rome, Italy

8. Department of Neuroscience and Rehabilitation, University of Ferrara and Center for Translational Neurophysiology of Speech and Communication (CTNSC), Italian Institute of Technology (IIT), 44121 Ferrara, Italy

9. Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, Italy

10. San Raffaele Institute of Sulmona, Viale dell’Agricoltura, 67039 Sulmona, Italy

Abstract

Determining the walking ability of post-stroke patients is crucial for the design of rehabilitation programs and the correct functional information to give to patients and their caregivers at their return home after a neurorehabilitation program. We aimed to assess the convergent validity of three different walking tests: the Functional Ambulation Category (FAC) test, the 10-m walking test (10MeWT) and the 6-minute walking test (6MWT). Eighty walking participants with stroke (34 F, age 64.54 ± 13.02 years) were classified according to the FAC score. Gait speed evaluation was performed with 10MeWT and 6MWT. The cut-off values for FAC and walking tests were calculated using a receiver-operating characteristic (ROC) curve. Area under the curve (AUC) and Youden’s index were used to find the cut-off value. Statistical differences were found in all FAC subgroups with respect to walking speed on short and long distances, and in the Rivermead Mobility Index and Barthel Index. Mid-level precision (AUC > 0.7; p < 0.05) was detected in the walking speed with respect to FAC score (III vs. IV and IV vs. V). The confusion matrix and the accuracy analysis showed that the most sensitive test was the 10MeWT, with cut-off values of 0.59 m/s and 1.02 m/s. Walking speed cut-offs of 0.59 and 1.02 m/s were assessed with the 10MeWT and can be used in FAC classification in patients with subacute stroke between the subgroups able to walk with supervision and independently on uniform and non-uniform surfaces. Moreover, the overlapping walking speed registered with the two tests, the 10MeWT showed a better accuracy to drive FAC classification.

Publisher

MDPI AG

Subject

General Neuroscience

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