Solution of a Complex Nonlinear Fractional Biochemical Reaction Model

Abstract

This paper discusses a complex nonlinear fractional model of enzyme inhibitor reaction where reaction memory is taken into account. Analytical expressions of the concentrations of enzyme, substrate, inhibitor, product, and other complex intermediate species are derived using Laplace decomposition and differential transformation methods. Since different rate constants, large initial concentrations, and large time domains are unavoidable in biochemical reactions, different dynamics will result; hence, the convergence of the approximate concentrations may be lost. In this case, the proposed analytical methods will be coupled with Padé approximation. The validity and accuracy of the derived analytical solutions will be established by direct comparison with numerical simulations.