Mathematical Modeling of the Drug Particles Deposition in the Human Respiratory System—Part 1: Development of Virtual Models of the Upper and Lower Respiratory Tract-Reference-Cited by-同舟云学术

Mathematical Modeling of the Drug Particles Deposition in the Human Respiratory System—Part 1: Development of Virtual Models of the Upper and Lower Respiratory Tract

Published:2024-07-01 Issue:7 Volume:12 Page:134
ISSN:2079-3197
Container-title:Computation
language:en
Short-container-title:Computation

Author:

Menshutina Natalia¹^ORCID,Mokhova Elizaveta¹,Abramov Andrey¹

Affiliation:

1. The Department of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russia

Abstract

In order to carry out mathematical modeling of the drug particles or drop movement in the human respiratory system, an approach to reverse prototyping of the studied areas based on the medical data (computed tomography) results is presented. To adapt the computational grid, a mathematical model of airflow in channels of complex geometry (respiratory system) has been developed. Based on the data obtained, the results of computational experiments for a single-phase system are presented.

Funder

Ministry of Science and Higher Education of the Russian Federation

Publisher

MDPI AG

Link

https://www.mdpi.com/2079-3197/12/7/134/pdf

Reference40 articles.

1. Olvera Lopez, E., Ballard, B.D., and Jan, A. (2024). Cardiovascular Disease. StatPearls, StatPearls Publishing.

2. The social determinants of tuberculosis: From evidence to action;Hargreaves;Am. J. Public Health,2011

3. World Health Organization (2018). Noncommunicable Diseases Country Profiles 2018, WHO Press. Available online: https://apps.who.int/iris/handle/10665/274512.

4. World Health Organization (2021). Global Tuberculosis Report 2021, WHO Press. Available online: https://www.who.int/publications/i/item/9789240037021.

5. World Health Organization (2022). Global Tuberculosis Report 2022, WHO Press. Available online: https://www.who.int/publications/i/item/9789240061729.