A New Mixed Fractional Derivative with Applications in Computational Biology

Author:

Hattaf Khalid12ORCID

Affiliation:

1. Equipe de Recherche en Modélisation et Enseignement des Mathématiques (ERMEM), Centre Régional des Métiers de l’Education et de la Formation (CRMEF), Derb Ghalef, Casablanca 20340, Morocco

2. Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M’Sick, Hassan II University of Casablanca, Sidi Othman, Casablanca P.O. Box 7955, Morocco

Abstract

This study develops a new definition of a fractional derivative that mixes the definitions of fractional derivatives with singular and non-singular kernels. This developed definition encompasses many types of fractional derivatives, such as the Riemann–Liouville and Caputo fractional derivatives for singular kernel types, as well as the Caputo–Fabrizio, the Atangana–Baleanu, and the generalized Hattaf fractional derivatives for non-singular kernel types. The associate fractional integral of the new mixed fractional derivative is rigorously introduced. Furthermore, a novel numerical scheme is developed to approximate the solutions of a class of fractional differential equations (FDEs) involving the mixed fractional derivative. Finally, an application in computational biology is presented.

Publisher

MDPI AG

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