Allantoin and Tissue Specific Redox Regulation in Mud Crab Scylla serrata under Varied Natural Water Physico-Chemical Parameters

Author:

Pati Samar Gourav12ORCID,Paital Biswaranjan1ORCID,Sahoo Dipak Kumar3ORCID

Affiliation:

1. Redox Regulation Laboratory, Department of Zoology, College of Basic Science and Humanities, Odisha University of Agriculture and Technology, Bhubaneswar 751003, India

2. Department of Zoology, School of Life Sciences, Ravenshaw University, Cuttack 753003, India

3. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA

Abstract

Effects of varied sediment and physico-chemical properties of water on allantoin content in tissues of Scylla serrata and its role in antioxidant homeostasis were investigated. Tissues of crabs were sampled from different coastal natural habitats of S. serrata of India during summer, winter, and rainy seasons and were analyzed to detect the variation in allantoin content and lipid peroxidation (LPx) and oxidative stress (OS) neutralizing antioxidant factors. High allantoin content in hepatopancreas over muscle tissue was observed in all seasons and sampling sites. The correlation coefficient values between allantoin and environmental factors, i.e., temperature, pH, salinity, organic carbon, Mg, and Ca, strongly support the stress-induced allantoin variation level in tissues. The level of allantoin had a negative correlation with levels of ROS, which was probably due to the upregulation of the activity of major antioxidant enzymes and assisting enzymes such as glutathione peroxidase (GPx), glutathione reductase (GR), and biotransforming enzyme glutathione -s- transferases (GST). A significant seasonal variation in the level of allantoin was correlated with the activity of including superoxide dismutase, catalase, GPx, GR, and GST, which was clearly noticed as a function of abiotic factors. Additionally, the level of allantoin did not correlate with small antioxidant molecules, such as ascorbic acid and reduced glutathione. Discriminant function analysis revealed that the level of allantoin and CAT and GR activities were the major contributing factors for the clear discrimination of groups. Therefore, allantoin can be considered as a significant factor for the seasonal modulation of OS physiology in mud crab Scylla serrata.

Funder

Science and Engineering Research Board, Department of Science and Technology, Govt. of India New Delhi, India

Department of Science and Technology, Government of Odisha

Publisher

MDPI AG

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