From Staining Techniques to Artificial Intelligence: A Review of Colorectal Polyps Characterization

Author:

Khalaf Kareem1ORCID,Fujiyoshi Mary Raina Angeli12ORCID,Spadaccini Marco34ORCID,Rizkala Tommy34,Ramai Daryl5,Colombo Matteo3,Fugazza Alessandro3ORCID,Facciorusso Antonio6ORCID,Carrara Silvia3,Hassan Cesare34,Repici Alessandro34

Affiliation:

1. Division of Gastroenterology, St. Michael’s Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada

2. Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo 135-8577, Japan

3. Department of Endoscopy, Humanitas Research Hospital, IRCCS, 20089 Rozzano, Italy

4. Department of Biomedical Sciences, Humanitas University, 20089 Rozzano, Italy

5. Gastroenterology and Hepatology, University of Utah Health, Salt Lake City, UT 84132, USA

6. Department of Endoscopy, Section of Gastroenterology, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy

Abstract

This review article provides a comprehensive overview of the evolving techniques in image-enhanced endoscopy (IEE) for the characterization of colorectal polyps, and the potential of artificial intelligence (AI) in revolutionizing the diagnostic accuracy of endoscopy. We discuss the historical use of dye-spray and virtual chromoendoscopy for the characterization of colorectal polyps, which are now being replaced with more advanced technologies. Specifically, we focus on the application of AI to create a “virtual biopsy” for the detection and characterization of colorectal polyps, with potential for replacing histopathological diagnosis. The incorporation of AI has the potential to provide an evolutionary learning system that aids in the diagnosis and management of patients with the best possible outcomes. A detailed analysis of the literature supporting AI-assisted diagnostic techniques for the detection and characterization of colorectal polyps, with a particular emphasis on AI’s characterization mechanism, is provided. The benefits of AI over traditional IEE techniques, including the reduction in human error in diagnosis, and its potential to provide an accurate diagnosis with similar accuracy to the gold standard are presented. However, the need for large-scale testing of AI in clinical practice and the importance of integrating patient data into the diagnostic process are acknowledged. In conclusion, the constant evolution of IEE technology and the potential for AI to revolutionize the field of endoscopy in the future are presented.

Publisher

MDPI AG

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