Cardiac Paraganglioma in a Young Patient Presents with Angina-like Symptoms: A Case Report and Literature Review

Author:

Alnahar Batool Wael1,Almiqlash Bushray2,Hassanain Hala3,Al-Najjar Ebtesam4,Esmail Abdullah4ORCID,Zainab Asma1,Ratnani Iqbal1

Affiliation:

1. Division of Cardiovascular ICU, Department of Critical Care Medicine, Houston Methodist Hospital, Houston, TX 77030, USA

2. Department of Cardiothoracic Surgery, Cincinnati Children’s Hospital, Cincinnati, OH 45229, USA

3. Department of Medicine, Houston Methodist Hospital, Houston, TX 77030, USA

4. Section of GI Oncology, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Houston, TX 77030, USA

Abstract

Paragangliomas are rare extra-adrenal neuroendocrine tumors originating from chromaffin tissue that present a diagnostic and therapeutic challenge due to their diverse clinical manifestations and low incidence. While these tumors often manifest as catecholamine-secreting functional tumors, their clinical presentation can vary, leading to delayed diagnosis and challenging management. This study presents the case of a 22-year-old patient with cardiac paraganglioma who initially presented with angina-like symptoms, highlighting the importance of considering this rare condition in young individuals with nonspecific complaints. Diagnostic imaging, including transthoracic echocardiography, CT angiography, and MRI, played a crucial role in identifying the tumor’s location and vascularization. Surgical excision, including pulmonary artery graft and CABG, was the primary management approach, which was accompanied by intraoperative complications that later led to CCU admission, followed by postoperative complications, ultimately leading to the patient’s death. This case highlights the significance of early recognition and management of complications following a surgical approach to treat paragangliomas.

Publisher

MDPI AG

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