The Association between Cafestol and Cardiovascular Diseases: A Comprehensive Review-Reference-Cited by-同舟云学术

The Association between Cafestol and Cardiovascular Diseases: A Comprehensive Review

Published:2024-05-26 Issue:6 Volume:60 Page:867
ISSN:1648-9144
Container-title:Medicina
language:en
Short-container-title:Medicina

Author:

Hao Wen-Rui¹²^ORCID,Cheng Chun-Yao³^ORCID,Chen Huan-Yuan⁴,Chen Jin-Jer⁴⁵,Cheng Tzu-Hurng⁶,Liu Ju-Chi¹²

Affiliation:

1. Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, New Taipei City 23561, Taiwan

2. Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11002, Taiwan

3. Department of Medical Education, National Taiwan University Hospital, Taipei 100225, Taiwan

4. Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan

5. Division of Cardiology, Department of Internal Medicine and Graduate Institute of Clinical Medical Science, China Medical University, Taichung City 115201, Taiwan

6. Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, Taichung City 404333, Taiwan

Abstract

Cafestol, a bioactive compound found in coffee, has attracted considerable attention due to its potential impact on cardiovascular health. This review aims to comprehensively explore the association between cafestol and cardiovascular diseases. We delve into the mechanisms through which cafestol influences lipid metabolism, inflammation, and endothelial function, all of which are pivotal in cardiovascular pathophysiology. Moreover, we meticulously analyze epidemiological studies and clinical trials to elucidate the relationship between cafestol and cardiovascular outcomes. Through a critical examination of existing literature, we aim to provide insights into the potential benefits and risks associated with cafestol concerning cardiovascular health.

Funder

National Science and Technology Council

Publisher

MDPI AG

Link

https://www.mdpi.com/1648-9144/60/6/867/pdf

Reference46 articles.

1. The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function;Fiani;Cureus,2021

2. Socala, K., Szopa, A., Serefko, A., Poleszak, E., and Wlaz, P. (2020). Neuroprotective Effects of Coffee Bioactive Compounds: A Review. Int. J. Mol. Sci., 22.

3. Coffee and cardiac arrhythmias: Up-date review of the literature and clinical studies;Surma;Cardiol. J.,2023

4. Cafestol Inhibits High-Glucose-Induced Cardiac Fibrosis in Cardiac Fibroblasts and Type 1-Like Diabetic Rats;Liu;Evid. Based Complement. Alternat. Med.,2020

5. Cafestol Activates Nuclear Factor Erythroid-2 Related Factor 2 and Inhibits Urotensin II-Induced Cardiomyocyte Hypertrophy;Hao;Am. J. Chin. Med.,2019