Abstract
Background and Objectives: To investigate the etiology, clinical features, ocular complications, and visual outcomes in children with infectious uveitis referred to a tertiary uveitis hospital-based service. Materials and Methods: Children with infectious uveitis were included in a retrospective cohort study. The data set was obtained after reviewing the medical records of pediatric patients with uveitis of different causes referred to our center during the period from 2009 to 2019. Clinical evaluations were performed at the time of diagnosis and the end of follow-up. Results: Uveitis of infectious origin was present in 57 (72 eyes) of 314 (18.1%) patients examined. The median age at presentation was 10.9 years (6.1–15.8), 52.6% of patients were female, and 47.4% were male. The main cause of infectious uveitis was viral (56.1% of cases), followed by Toxoplasma gondii infection (24.5%). The anatomical location of uveitis was posterior in 40.3%, anterior in 36.8%, panuveitis in 15.7%, and intermediate in 7% of cases. Ocular involvement was unilateral in 42 children (73.7%) and bilateral in 15 (26.3%) cases. The main causes of reduced visual acuity were cataract and maculopathy in 57.1% and 28.5% of cases, respectively. During the follow-up period, 75% of patients showed significant improvements in visual acuity. Conclusions: Specialist management in a tertiary referral eye care center facilitates early diagnosis and effective treatment of this serious cause of morbidity and vision loss in children.
Reference40 articles.
1. Pediatric uveitis;J. Ophthalmic Vis. Res.,2011
2. Changes in patterns of uveitis at a tertiary referral center in Northern Italy: Analysis of 990 consecutive cases;Int. Ophthalmol.,2018
3. Incidence and prevalence of uveitis: Results from the Pacific Ocular Inflammation Study;JAMA Ophthalmol.,2013
4. Infectious involvement in a tertiary center pediatric uveitis cohort;Br. J. Ophthalmol.,2015
5. Patterns of childhood-onset uveitis in a referral center in Turkey;J. Ophthalmic Inflamm. Infect.,2012
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Pediatric Posterior Infectious Uveitis;Ocular Immunology and Inflammation;2023-11-26