Olfactory Neuroblastoma—A Challenging Fine Line between Metastasis and Hematology

Author:

Marina Trandafir Cornelia1,Constantin Balica Nicolae12,Flavia Baderca3ORCID,Silvana Sarau Oana4,Marioara Poenaru1,Sarau Cristian Andrei5ORCID

Affiliation:

1. ENT Department, Spitalul Clinic Municipal de Urgenta, Victor Babeş University of Medicine and Pharmacy, Bulevardul. Revolutiei No. 6, 300054 Timisoara, Romania

2. ENT Department, Victor Babeş University of Medicine and Pharmacy, 300041 Timişoara, Romania

3. Department of Microscopic Morphology, Victor Babeş University of Medicine and Pharmacy, 300041 Timişoara, Romania

4. Department of Hematology, Victor Babeş University of Medicine and Pharmacy, 300041 Timisoara, Romania

5. Department of Medical Semiology I, Victor Babeş University of Medicine and Pharmacy, 300041 Timişoara, Romania

Abstract

Developing in a limited space, rare tumors located at the nose and paranasal sinuses are sometimes difficult to diagnose due to their modest clinical presentation, which is uncorrelated with anatomopathological diversity. This limits the preoperative diagnosis without added immune histochemical study; for that reason, we present our experience with these tumors with the intention of raising awareness. The patient included in our study was investigated by our department through clinical and endoscopic examination, imaging investigations, and an anatomic-pathological study. The selected patient gave consent for participation and inclusion in this research study in compliance with the 1964 Declaration of Helsinki.

Publisher

MDPI AG

Subject

General Medicine

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