Primary Effusion Lymphoma, Multicentric Castleman’s Disease, and Kaposi’s Sarcoma in an HHV-8 and HIV-Positive Patient: A Case Report

Author:

Caballero Juan Carlos1,Pardo Laura1ORCID,Rodriguez-Pinilla Maria Socorro2,Piris Miguel Angel2ORCID,Alvarez Beatriz3,Solan Laura1ORCID,Cornago Javier1ORCID,Lopez-Lorenzo Jose Luis1ORCID,Llamas Pilar1,Cordoba Raul1ORCID,Lopez-Garcia Alberto1ORCID

Affiliation:

1. Department of Hematology, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain

2. Department of Pathology, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain

3. Department of Internal Medicine, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain

Abstract

Primary effusion lymphoma (PEL), Kaposi’s sarcoma (KS), and multicentric Castleman’s disease (MCD) is an uncommon group of diseases included in the same spectrum with related characteristics. The coexistence of all of them in the same individual is a rare occurrence. We present the case of a 25-year-old patient diagnosed with human immunodeficiency virus (HIV) and the development of all these related pathologies. Despite the use of intensive treatment according to the latest recommendations, the evolution was unfavorable. This case reflects the need for new therapies and research in this field.

Publisher

MDPI AG

Subject

General Medicine

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