A Comparative Analysis between Enhanced Recovery after Surgery and Traditional Care in the Management of Obstructive Colorectal Cancer

Author:

Mihăilescu Alexandra-Ana12,Onisâi Minodora13ORCID,Alexandru Adrian14,Teodorescu Matei15,Aliuș Cătălin16,Blendea Corneliu-Dan78,Neagu Ștefan-Ilie1,Șerban Dragoș16ORCID,Grădinaru Sebastian79

Affiliation:

1. Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania

2. Department of Anesthesiology and Intensive Care Unit, Foisor Hospital Bucharest, 030167 Bucharest, Romania

3. Hematology Department, Emergency University Hospital Bucharest, 050098 Bucharest, Romania

4. Department of Plastic and Reconstructive Surgery, Emergency University Hospital Bucharest, 050098 Bucharest, Romania

5. Neurological Recovery Clinic, Elias University Emergency Hospital, 011461 Bucharest, Romania

6. 4th Surgery Department, Emergency University Hospital Bucharest, 050098 Bucharest, Romania

7. Faculty of Medicine, Titu Maiorescu University, 040441 Bucharest, Romania

8. Department of Recovery, Physical Medicine and Balneology, Ilfov County Emergency Clinical Hospital, 022104 Bucharest, Romania

9. Department of General Surgery, Ilfov County Emergency Clinical Hospital, 022104 Bucharest, Romania

Abstract

Enhanced Recovery After Surgery (ERAS) represents evidence-based transformation in perioperative care, which has been demonstrated to reduce both recovery times and postoperative complication rates. The aim of the present study was to evaluate the clinical significance of the ERAS program in comparison with conventional postoperative care. This longitudinal cohort observational study enrolled 120 consecutive patients diagnosed with intestinal obstruction caused by colorectal cancers, with 40 patients in the ERAS group and 80 patients receiving conventional postoperative care forming the non-ERAS group. Our study compares the effectiveness of ERAS protocols to non-ERAS methods, focusing on the time to first flatus, defecation, the resumption of normal diet, and early mobilization. The main endpoints are morbidity and hospitalization length. The results showed that despite a longer admission-to-surgery interval in the ERAS group, median hospitalization was significantly shorter compared to the non-ERAS group (p = 0.0002). The ERAS group showed a tendency towards a lower incidence of overall postoperative complications, indicating that implementing the ERAS protocol does not increase the risk of postoperative complications, ensuring the safety of enhanced recovery strategies for patients. Also, ERAS patients had notably fewer stomas than those in the non-ERAS group, indicating the potential effectiveness of reducing stoma necessity. This study shows that ERAS surpasses conventional care for colonic or rectal surgery patients, reducing hospital stays and costs while enhancing recovery. This highlights the comprehensive advantages of adopting ERAS in surgical settings.

Publisher

MDPI AG

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