Impact of Intraoperative Factors on the Development of Postpartum Septic Complications

Author:

Andzane Diana1234,Miskova Anna134ORCID,Krone Antra1,Rezeberga Dace123ORCID

Affiliation:

1. Riga Maternity Hospital, Miera Street 45, LV-1013 Riga, Latvia

2. Gynaecology Clinic, Riga East Clinical University Hospital, Hipokrata Street 2, LV-1079 Riga, Latvia

3. Department of Obstetrics and Gynaecology, Rīga Stradiņš University, Miera Street 45, LV-1013 Riga, Latvia

4. Department of Clinical Skills and Medical Technologies, Rīga Stradiņš University, Anninmuizas Bulvaris 26a, LV-1067 Riga, Latvia

Abstract

Background and Objectives: Triclosan-coated sutures (antibacterial sutures) can reduce the risk of postoperative surgical site infection. This study aimed to investigate the effect of intraoperative factors, including antibacterial sutures, on the risk of postpartum septic complications. Materials and Methods: The prospective study included patients who underwent caesarean section. The exclusion criterion was chorioamnionitis. The investigation group patient’s (n = 67) uterus and fascial sheath of the abdominal wall were sutured with triclosan-coated polyglactin 910 sutures during surgery. The control group consisted of 98 patients using uncoated polyglactin 910 sutures only. The patients were contacted by phone after the 30th postoperative day. Results: No significant difference was found between the investigation group and the control group in the development of postpartum endometritis (11.7% in the investigation group vs. 8.4% in the control group, p = 0.401), wound infection (6.3% vs. 3.6%, p = 0.444) or patients experienced any septic complication (15.9% vs. 12%, p = 0.506). Postpartum endometritis was more common in patients who underwent instrumental uterine examination during the surgery (23.8% vs. 18%, p = 0.043). A moderately strong correlation was found for haemoglobin level on the third–fourth postoperative day with the development of postpartum septic complications, p < 0.001, Pearson coefficient −0.319. Post-caesarean delivery septic complications were not statistically more common in patients with blood loss greater than 1 L. The incidence of post-caesarean endometritis was 13.4%, and wound infection was 4.8% in this study’s hospital, having five to six thousand deliveries per year. Conclusions: Using antibacterial sutures during caesarean section does not affect the incidence of postpartum septic complications. Instrumental uterine examination during caesarean section increases the risk of post-caesarean endometritis and is, therefore, not recommended. Haemoglobin level on the 3rd–4th postoperative day, rather than the estimated blood loss during surgery, affects the development of postpartum septic complications.

Publisher

MDPI AG

Subject

General Medicine

Reference43 articles.

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2. DeCherney, A.H., Nathan, L., Laufer, N., and Roman, A.S. (2019). CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, McGraw-Hill Education. [12th ed.].

3. Surgical Site Infections after Cesarean Delivery: Epidemiology, Prevention and Treatment;Kawakita;Matern. Health Neonatol. Perinatol.,2017

4. Endometritis;Taylor;Br. Med. J.,2022

5. Puerperal Infections of the Genital Tract: A Clinical Review;Karsnitz;J. Midwifery Womens Health,2013

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