Significance of operative parameters on outcomes after transurethral resection of the prostate

Abstract

Objective. The aim of this prospective study was to establish the influence of operative parameters on outcomes after transurethral resection of the prostate. Materials and methods. In this prospective case series study, 89 patients underwent transurethral resection of the prostate. The standardized protocol was used to investigate the impact of operative parameters (resected tissue weight, residual prostate weight, and residual prostatic weight ratio [total prostate volume – resected tissue weight / total prostate volume]) on outcomes after six months following transurethral resection of the prostate. The evaluation of treatment efficacy was done using the criteria of the Second International Consultation on Benign Prostatic Hyperplasia. All postoperative results were categorized as excellent, good, fair, or none. Treatment was considered effective when the postoperative results were excellent and good, and ineffective when results were fair and none. Results. Treatment was effective for 85.4% and ineffective for 14.6% of the patients. The univariate analysis of operative parameters detected the residual prostatic weight ratio (cutoff value, 0.71; P<0.001; sensitivity, 0.62; specificity, 0.96; OR, 39.47) as the strongest independent predictor of ineffective outcome. Logistic regression analysis revealed two important parameters of unfavorable outcomes: residual prostatic weight ratio (cutoff value, 0.71; P<0.001; OR, 62.16) and residual prostate weight (cutoff value, 26.6 mL; P=0.013; OR, 9.98). When the values of both these parameters were lower than their cutoff values, the probability of an ineffective outcome was reduced to 3%; however, when they were higher, the probability of an unfavorable outcome was increased to 95%. Conclusions. Residual prostatic weight ratio and residual prostatic weight are significant operative parameters for the prediction of outcomes after transurethral resection of the prostate.