Left-Side Contrast-Injection-Induced Pseudopathologic Vertebral Enhancement in Oncology Patients without Venous Obstruction: A Report of Two Cases

Author:

Bae Kyungsoo12,Moon Jin Il12,Jeon Kyung Nyeo12ORCID

Affiliation:

1. Department of Radiology, Institute of Medical Science, Gyeongsang National University School of Medicine, Jinju 52727, Republic of Korea

2. Department of Radiology, Gyeongsang National University Changwon Hospital, Changwon 51472, Republic of Korea

Abstract

The appearance of sclerotic bone lesions in contrast-enhanced computed tomography (CT) scans is often a significant concern for the possible presence of metastatic disease, especially in individuals with a known history of cancer. Prior research has demonstrated that in cases where patients suffer from thrombosis in major veins like the superior vena cava or the brachiocephalic vein, vertebral venous congestion can create imaging patterns on CT scans that resemble sclerotic bone metastases. However, instances of such imaging findings in patients without any form of venous obstruction are not commonly reported. In this study, we present cases of pseudopathologic vertebral enhancement observed consistently following left-side contrast injections in cancer patients devoid of venous obstruction. We aim to discuss and propose a potential mechanism for this phenomenon, drawing attention to a less commonly recognized diagnostic consideration in oncological imaging.

Publisher

MDPI AG

Subject

General Medicine

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