Two Different Tumors and Lung Aspergilloma: An Uncommon Etiopathogenic Association

Author:

Ionescu Vlad Alexandru12,Gheorghe Gina12,Adrian Cosmin3,Bebliuc Alexandru4,Pavelescu Cezar4,Enache Valentin5,Gheorghe Florentina6,Bacalbasa Nicolae78,Diaconu Camelia Cristina129ORCID

Affiliation:

1. Faculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, Romania

2. Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

3. Department of Radiology, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

4. Department of Thoracic Surgery, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

5. Department of Anatomical Pathology, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

6. Department of Biochemistry, Synevo Romania, 077040 Chiajna, Romania

7. Department of Surgery, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, Romania

8. Department of Surgery, Center of Excellence in Translational Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania

9. Academy of Romanian Scientists, 050045 Bucharest, Romania

Abstract

Several cases reported in the literature have confirmed the link between pulmonary aspergillosis and various malignant diseases. Furthermore, it has been observed that the correlation between carcinoid tumor and lung adenocarcinoma is quite uncommon. The etiopathogenic mechanisms underlying these correlations remain poorly defined. We present the case of a patient with three of these diseases: a lung adenocarcinoma with a lepidic pattern, a typical carcinoid, and pulmonary aspergillosis. An additional noteworthy aspect of this case pertains to the timely detection of both lung malignancies. Thus, the necessity for further investigation to ascertain the pathogenic connection among the three diseases is underscored. The ultimate objective is to enhance the prognosis of individuals diagnosed with lung cancer, which is a prevailing malignant disease on a global scale.

Publisher

MDPI AG

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