Validity and Sensitivity of an Inertial Measurement Unit-Driven Biomechanical Model of Motor Variability for Gait

Abstract

Motor variability in gait is frequently linked to fall risk, yet field-based biomechanical joint evaluations are scarce. We evaluated the validity and sensitivity of an inertial measurement unit (IMU)-driven biomechanical model of joint angle variability for gait. Fourteen healthy young adults completed seven-minute trials of treadmill gait at several speeds and arm swing amplitudes. Trunk, pelvis, and lower-limb joint kinematics were estimated by IMU- and optoelectronic-based models using OpenSim. We calculated range of motion (ROM), magnitude of variability (meanSD), local dynamic stability (λmax), persistence of ROM fluctuations (DFAα), and regularity (SaEn) of each angle over 200 continuous strides, and evaluated model accuracy (RMSD: root mean square difference), consistency (ICC2,1: intraclass correlation), biases, limits of agreement, and sensitivity to within-participant gait responses (effects of speed and swing). RMSDs of joint angles were 1.7–9.2° (pooled mean of 4.8°), excluding ankle inversion. ICCs were mostly good to excellent in the primary plane of motion for ROM and in all planes for meanSD and λmax, but were poor to moderate for DFAα and SaEn. Modelled speed and swing responses for ROM, meanSD, and λmax were similar. Results suggest that the IMU-driven model is valid and sensitive for field-based assessments of joint angle time series, ROM in the primary plane of motion, magnitude of variability, and local dynamic stability.