1. Department of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology “G.A. Maccacaro”, Università degli Studi di Milano, 20133 Milan, Italy
2. Department of Biochemical, Surgical & Dental Sciences, Università degli Studi di Milano, 20122 Milan, Italy
3. Istituto Clinico Città Studi, 20131 Milan, Italy
4. Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy
5. Laboratory of Biostatistics and Data Management, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milan, Italy