Affiliation:
1. Department of Analytical Chemistry, University of Vienna, Währinger Straße 38, A-1090 Vienna, Austria
2. School of Chemistry, University of the Punjab, Quaid-i-Azam Campus, Lahore 54590, Pakistan
Abstract
This perspective article focuses on the overwhelming significance of molecular recognition in biological processes and its emulation in synthetic molecules and polymers for chemical sensing. The historical journey, from early investigations into enzyme catalysis and antibody–antigen interactions to Nobel Prize-winning breakthroughs in supramolecular chemistry, emphasizes the development of tailored molecular recognition materials. The discovery of supramolecular chemistry and molecular imprinting, as a versatile method for mimicking biological recognition, is discussed. The ability of supramolecular structures to develop selective host–guest interactions and the flexible design of molecularly imprinted polymers (MIPs) are highlighted, discussing their applications in chemical sensing. MIPs, mimicking the selectivity of natural receptors, offer advantages like rapid synthesis and cost-effectiveness. Finally, addressing major challenges in the field, this article summarizes the advancement of molecular recognition-based systems for chemical sensing and their transformative potential.
Subject
Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry
Reference45 articles.
1. A Theory of the Structure and Process of Formation of Antibodies*;Pauling;J. Am. Chem. Soc.,1940
2. The Design of Molecular Hosts, Guests, and Their Complexes (Nobel Lecture);Cram;Angew. Chem. Int. Ed. Engl.,1988
3. Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices(Nobel Lecture);Lehn;Angew. Chem. Int. Ed. Engl.,1988
4. The Discovery of Crown Ethers (Noble Lecture);Pedersen;Angew. Chem. Int. Ed. Engl.,1988
5. Healy, B., Yu, T., Alves, D.C.d.S., Okeke, C., and Breslin, C.B. (2021). Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors. Materials, 14.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献