Adoption of Transformer Neural Network to Improve the Diagnostic Performance of Oximetry for Obstructive Sleep Apnea

Author:

Almarshad Malak Abdullah12ORCID,Al-Ahmadi Saad1ORCID,Islam Md Saiful1ORCID,BaHammam Ahmed S.34ORCID,Soudani Adel1ORCID

Affiliation:

1. Computer Science Department, College of Computer and Information Sciences, King Saud University, Riyadh 11543, Saudi Arabia

2. Computer Science Department, College of Computer and Information Sciences, Al-Imam Mohammad Ibn Saud Islamic University, Riyadh 11432, Saudi Arabia

3. The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh 11324, Saudi Arabia

4. Strategic Technologies Program of the National Plan for Sciences and Technology and Innovation in the Kingdom of Saudi Arabia, Riyadh 11324, Saudi Arabia

Abstract

Scoring polysomnography for obstructive sleep apnea diagnosis is a laborious, long, and costly process. Machine learning approaches, such as deep neural networks, can reduce scoring time and costs. However, most methods require prior filtering and preprocessing of the raw signal. Our work presents a novel method for diagnosing obstructive sleep apnea using a transformer neural network with learnable positional encoding, which outperforms existing state-of-the-art solutions. This approach has the potential to improve the diagnostic performance of oximetry for obstructive sleep apnea and reduce the time and costs associated with traditional polysomnography. Contrary to existing approaches, our approach performs annotations at one-second granularity. Allowing physicians to interpret the model’s outcome. In addition, we tested different positional encoding designs as the first layer of the model, and the best results were achieved using a learnable positional encoding based on an autoencoder with structural novelty. In addition, we tried different temporal resolutions with various granularity levels from 1 to 360 s. All experiments were carried out on an independent test set from the public OSASUD dataset and showed that our approach outperforms current state-of-the-art solutions with a satisfactory AUC of 0.89, accuracy of 0.80, and F1-score of 0.79.

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

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