Affiliation:
1. Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry RAS, 142432 Chernogolovka, Russia
2. Scientific Center in Chernogolovka, The Institute of Solid State Physics RAS, 142432 Chernogolovka, Russia
Abstract
This review presents the results of studies of molecular exchange processes in various biological systems (erythrocytes, yeast, liposomes, etc.) performed using pulsed field gradient NMR (PFG NMR). The main theory of processing necessary for the analysis of experimental data is briefly presented: the extraction of self-diffusion coefficients, calculation of cell sizes, and permeability of cell membranes. Attention is paid to the results of assessing the permeability of biological membranes for water molecules and biologically active compounds. The results for other systems are also presented: yeast, chlorella, and plant cells. The results of studies of the lateral diffusion of lipid and cholesterol molecules in model bilayers are also presented.
Funder
Ministry of Education and Science of the Russian Federation
Subject
Filtration and Separation,Chemical Engineering (miscellaneous),Process Chemistry and Technology
Reference58 articles.
1. Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., and Walter, P. (2002). Molecular Biology of the Cell, Garland Science. [4th ed.].
2. The fluid mosaic model of the structure of cell;Singer;Science,1972
3. Heitjans, P., and Karger, J. (2005). Diffusion in Condensed Matte, Springer.
4. Yeagle, P.L. (2016). The Membranes of Cells, Academic Press. [3rd ed.].
5. Membrane transport;Antonov;Sorosovskii Obraz. Zhurnal,1997
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献