Antimicrobial Activity of Polycaprolactone Nanofiber Coated with Lavender and Neem Oil Nanoemulsions against Airborne Bacteria-Reference-Cited by-同舟云学术

Antimicrobial Activity of Polycaprolactone Nanofiber Coated with Lavender and Neem Oil Nanoemulsions against Airborne Bacteria

Published:2024-01-29 Issue:2 Volume:14 Page:36
ISSN:2077-0375
Container-title:Membranes
language:en
Short-container-title:Membranes

Author:

Rahman Md Mahfuzur¹^ORCID,Kotturi Hari²^ORCID,Nikfarjam Sadegh²^ORCID,Bhargava Kanika¹,Ahsan Nagib³⁴,Khandaker Morshed⁵^ORCID

Affiliation:

1. Department of Human Environmental Sciences, University of Central Oklahoma, Edmond, OK 73034, USA

2. Department of Biology, University of Central Oklahoma, Edmond, OK 73034, USA

3. Department of Chemistry and Biochemistry, The University of Oklahoma, Norman, OK 73019, USA

4. Mass Spectrometry, Proteomics and Metabolomics Core Facility, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019, USA

5. Nanobiology Laboratory, School of Engineering, University of Central Oklahoma, Edmond, OK 73034, USA

Abstract

The development of efficient, eco-friendly antimicrobial agents for air purification and disinfection addresses public health issues connected to preventing airborne pathogens. Herein, the antimicrobial activity of a nanoemulsion (control, 5%, 10%, and 15%) containing neem and lavender oils with polycaprolactone (PCL) was investigated against airborne bacteria, including Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Various parameters such as the physicochemical properties of the nanoemulsion, pH, droplet size, the polydispersity index (PDI), the minimum inhibitory concentration (MIC), the minimum bacterial concentration (MBC), and the color measurement of the emulsion have been evaluated and optimized. Our results showed that the antimicrobial activity of PCL combined with neem and lavender oil was found to be the highest MIC and MBC against all tested bacteria. The droplet sizes for lavender oil are 21.86–115.15 nm, the droplet sizes for neem oil are 23.92–119.15 nm, and their combination is 25.97–50.22 nm. The range of pH and viscosity of nanoemulsions of various concentrations was found to be 5.8 to 6.6 pH and 0.372 to 2.101 cP. This study highlights the potential of nanotechnology in harnessing the antimicrobial properties of natural essential oils, paving the way for innovative and sustainable solutions in the fight against bacterial contamination.

Funder

ENF Products, LLC

CURE-STEM, faculty on campus grant

Student Research and Sponsored Programs (RCSA) Grant Programs

Publisher

MDPI AG

Link

https://www.mdpi.com/2077-0375/14/2/36/pdf

Reference31 articles.

1. Neem oil and its nanoemulsion in sustainable food preservation and packaging: Current status and future prospects;Kumar;J. Agric. Food Res.,2022

2. Neem oil based nano-emulsion formulation by low energy phase inversion composition method: Characterization and antimicrobial activity;Safaya;Mater. Today Proc.,2022

3. Development of Bio nanocomposites of pectin and nanoemulsions of carnauba wax and neem oil pectin/carnauba wax/neem oil composites;Pereira;Polym. Compos.,2020

4. Characterization, antimicrobial activity, and antioxidant activity of the nanoemulsions of Lavandula spica essential oil and its main monoterpenes;Badr;J. Drug Deliv. Sci. Technol.,2021

5. Mossa, A.T.H., Mohamed, R.I., and Mohafrash, S.M. (2022). Development of a ‘green’nanoformulation of neem oil-based nanoemulsion for controlling mosquitoes in the sustainable ecosystem. Biocatal. Agric. Biotechnol., 46.