A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men

Author:

Chirca Narcis12,Streinu-Cercel Anca13,Stefan Marius4,Aurelian Justin12,Persu Cristian12ORCID

Affiliation:

1. “Carol Davila” University of Medicine and Pharmacy, Str. Vasile Lascar, Nr. 37, Sector 3, 035648 Bucharest, Romania

2. Department of Urology, “Prof. Dr. Th. Burghele” Clinical Hospital, Sos. Panduri Nr. 20, Sector 5, 05324 Bucharest, Romania

3. National Institute of Infectious Diseases “Prof. Dr. Matei Bals”, Str. Doctor Calistrat Grozovici, Sector 1, 021105 Bucharest, Romania

4. Faculty of Applied Sciences, Polytechnic University of Bucharest, Splaiul Independentei Nr. 313, Sala BN108, Sector 6, 060042 Bucharest, Romania

Abstract

HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quality of life. The aim of this paper is to evaluate the presence of ED in HIV-positive men and the associated contributing factors and to create a statistical model to assess the risk to develop ED in this population. In a prospective study, we analyzed a group of HIV-positive men in a cross-sectional manner, looking at demographics, blood test results, and smoking habits. Data were statistically analyzed using the Kruskal–Wallis test. In our series, the overall incidence of ED was 48.5%, increasing with age. Our analysis showed no correlation with blood sugar level, but a very strong correlation with total serum lipids. We were able to develop and validate a risk calculator for ED in HIV-positive men.

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

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