REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia

Author:

Barcessat Ana Rita Pinheiro12,Nunes Lucas dos Santos1,Gonçalves Rebeca Góes1,Darienso Danyela3

Affiliation:

1. Health and Biological Sciences Department, Federal University of Amapá, Macapá 68900-350, Brazil

2. Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy

3. Health Science Post Graduate Program-PPGCS–UNIFAP, Federal University of Amapá, Macapá 68900-350, Brazil

Abstract

Background: Chronic post-herpetic neuralgia (CPHN) is a symptomatic condition that afflicts adults and elderly individuals. The chronicity of this symptomatology can be conditioned by the epigenetic modifications induced by the virus on the processes of neurotransmission and sensitivity to pain. The aim of this study is to investigate whether manipulating endogenous bioelectrical activity (EBA), responsible for neurotransmission processes and contributing to the induction of epigenetic modifications, can alleviate pain symptoms. Methods: This manipulation was carried out with the antalgic neuromodulation (ANM) treatment of radioelectric asymmetric conveyer (REAC) technology. Pain assessment before and after treatment was performed using a numerical analog scale (NAS) and a simple descriptive scale (SDS). Results: The results of the analysis showed an over four-point decrease in NAS scale score and over one point decrease in SDS scale score, with a statistical significance for both tests of p < 0.005. Conclusions: The results obtained in this study demonstrate how REAC ANM manipulation of EBA can lead to improvement in epigenetically conditioned symptoms such as CPHN. These results should prompt further research to expand knowledge and ensure optimized therapeutic outcomes.

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

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