ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome
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Published:2021-12-31
Issue:1
Volume:11
Page:224
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ISSN:2077-0383
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Container-title:Journal of Clinical Medicine
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language:en
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Short-container-title:JCM
Author:
Martin-Loeches IgnacioORCID, Motos Anna, Menéndez Rosario, Gabarrús Albert, González Jessica, Fernández-Barat LaiaORCID, Ceccato AdriánORCID, Pérez-Arnal RaquelORCID, García-Gasulla DarioORCID, Ferrer RicardORCID, Riera Jordi, Lorente José, Peñuelas Óscar, Bermejo-Martin Jesús, de Gonzalo-Calvo David, Rodríguez Alejandro, Barbé Ferran, Aguilera Luciano, Amaya-Villar Rosario, Barberà Carme, Barberán José, Blandino Ortiz AaronORCID, Bustamante-Munguira Elena, Caballero Jesús, Carbajales CristinaORCID, Carbonell NievesORCID, Catalán-González Mercedes, Galbán Cristóbal, Gumucio-Sanguino Víctor, de la Torre Maria, Díaz EmiliORCID, Gallego Elena, García Garmendia JoséORCID, Garnacho-Montero JoséORCID, Gómez José, Jorge García Ruth, Loza-Vázquez Ana, Marín-Corral Judith, Martínez de la Gándara Amalia, Martínez Varela Ignacio, Lopez Messa Juan, Albaiceta Guillermo, Novo Mariana, Peñasco Yhivian, Ricart Pilar, Urrelo-Cerrón Luis, Sánchez-Miralles Angel, Sancho Chinesta Susana, Socias Lorenzo, Solé-Violan JordiORCID, Tamayo Lomas Luis, Vidal PabloORCID, Torres AntoniORCID
Abstract
Background. Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to non-critically ill patients, less is known about the incidence and factors associated with the characteristics of persistent COVID-19. On the other hand, these patients very often have intensive care unit-acquired pneumonia (ICUAP). A second infectious hit after COVID increases the length of ICU stay and mechanical ventilation and could have an influence on poor health post-COVID 19 syndrome in ICU-discharged patients. Methods: This prospective, multicentre, and observational study was carrid out across 40 selected ICUs in Spain. Consecutive patients with COVID-19 requiring ICU admission were recruited and evaluated three months after hospital discharge. Results: A total of 1255 ICU patients were scheduled to be followed up at 3 months; however, the final cohort comprised 991 (78.9%) patients. A total of 315 patients developed ICUAP (97% of them had ventilated ICUAP). Patients requiring invasive mechanical ventilation had more persistent post-COVID-19 symptoms than those who did not require mechanical ventilation. Female sex, duration of ICU stay, development of ICUAP, and ARDS were independent factors for persistent poor health post-COVID-19. Conclusions: Persistent post-COVID-19 symptoms occurred in more than two-thirds of patients. Female sex, duration of ICU stay, development of ICUAP, and ARDS all comprised independent factors for persistent poor health post-COVID-19. Prevention of ICUAP could have beneficial effects in poor health post-COVID-19.
Funder
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
Cited by
13 articles.
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