Abstract
Normal-weight obesity (NWO) is a phenotype characterized by excessive body fat (BF) despite normal body weight. We aimed to assess the association between NWO and the risk of sarcopenia. Two groups of patients with a normal body mass index [BMI (20–24.9 kg/m2)] were selected from a large cohort of participants. Body composition was measured using dual-energy X-ray absorptiometry (DXA), and 748 participants were categorized as NWO or normal-weight without obesity (NWNO) and were classed according to whether or not they were at risk of sarcopenia. The “NWO group” included 374 participants (cases), compared to 374 participants (controls) in the “NWNO group”, all of a similar BMI, age and gender. The participants in the “NWO group” displayed a higher prevalence of the risk of sarcopenia than the control group across both genders (0.6% vs. 14.1% in males; 1.4% vs. 36.5% in females). Regression analysis showed that being in the NWO category increased the risk of sarcopenia 22-fold in males (RR = 22.27; 95%CI: 3.35–147.98) and 25-fold in females (RR = 25.22; 95%CI: 8.12–78.36), compared to those in the NWNO category. In a “real-world” nutritional setting, the assessment of body composition to identify NWO syndrome is vital since it is also associated with a higher risk of sarcopenia.
Subject
Food Science,Nutrition and Dietetics
Reference41 articles.
1. A 2022 update on the epidemiology of obesity and a call to action: As its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on;Boutari;Metabolism,2022
2. The medical risks of obesity;Postgrad. Med.,2009
3. Impact of obesity on disability, function, and physical activity: Data from the Osteoarthritis Initiative;Batsis;Scand. J. Rheumatol.,2015
4. The Psychosocial Burden of Obesity;Sarwer;Endocrinol. Metab. Clin. N. Am.,2016
5. Overweight, obesity, and depression: A systematic review and meta-analysis of longitudinal studies;Luppino;Arch. Gen. Psychiatry,2010
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献