Artificial-Intelligence-Based Models Coupled with Correspondence Analysis Visualization on ART—Cases from Gombe State, Nigeria: A Comparative Study
Author:
Bala Kabiru12, Etikan Ilker1ORCID, Usman A. G.34ORCID, Abba S. I.5
Affiliation:
1. Biostatistics Department, Faculty of Medicine, Near East University, 99138 Nicosia, Cyprus 2. Taraba State Polytechnic Suntai, Jalingo Campus, Howayi 660213, Taraba, Nigeria 3. Operational Research Centre in Healthcare, Near East University, 99138 Nicosia, Cyprus 4. Department of Analytical Chemistry, Faculty of Pharmacy, Near East University, 99138 Nicosia, Cyprus 5. Interdisciplinary Research Centre for Membrane and Water Security, Faculty of Petroleum and Minerals, King Fahd University, Dhahran 31261, Saudi Arabia
Abstract
Antiretroviral therapy (ART) is the common hope for HIV/AIDS-treated patients. Total commitments from individuals and the entire community are the major challenges faced during treatment. This study investigated the progress of ART in the Federal Teaching Hospital in Gombe state, Nigeria by using various records of patients receiving treatment in the ART hospital unit. We combined artificial intelligence (AI)-based models and correspondence analysis (CA) techniques to predict and visualize the progress of ART from the beginning to the end. The AI models employed are artificial neural networks (ANNs), adaptive neuro-fuzzy inference systems (ANFISs) and support-vector machines (SVMs) and a classical linear regression model of multiple linear regression (MLR). According to the outcome of this study, ANFIS in both training and testing outperformed the remaining models given the R2 (0.903 and 0.904) and MSE (7.961 and 3.751) values, revealing that any increase in the number of years of taking ART medication will provide HIV/AIDS-treated patients with safer and elongated lives. The contingency results for the CA and the chi-square test did an excellent job of capturing and visualizing the patients on medication, which gave similar results in return, revealing there is a significant association between ART drugs and the age group, while the association between ART drugs and marital status (93.7%) explained a higher percentage of variation compared with the remaining variables.
Subject
Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics
Reference31 articles.
1. De Vito, A., Colpani, A., Saderi, L., Puci, M., Zauli, B., Fiore, V., Fois, M., Meloni, M.C., Bitti, A., and Di Castri, C. (2023). Impact of Early SARS-CoV-2 Antiviral Therapy on Disease Progression. Viruses, 15. 2. Toska, E., Zhou, S., Chen-Charles, J., Gittings, L., Operario, D., and Cluver, L. (2023). Factors Associated with Preferences for Long-Acting Injectable Antiretroviral Therapy Among Adolescents and Young People Living with HIV in South Africa. AIDS Behav. 3. Association of Race and Ethnicity with Initial Prescription of Antiretroviral Therapy Among People with HIV in the US;Zalla;JAMA,2023 4. Li, S., Ouyang, J., Zhao, B., An, M., Wang, L., Ding, H., Zhang, M., and Han, X. (2020). The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains. BMC Infect. Dis., 20. 5. Torres, M.C., Gómez, M., Schjetnan, P., Terán, G.R., Briceño, O., Ríos, S.Á., Alejandra, K., Mora, R., and Cardoso, S.P. (2023). The vaginal microbiota of women living with HIV on suppressive antiretroviral therapy and its relation to high-risk human papillomavirus infection. BMC Microbiol., 23.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|