Cognitive Fitness: Harnessing the Strength of Exerkines for Aging and Metabolic Challenges-Reference-Cited by-同舟云学术

Cognitive Fitness: Harnessing the Strength of Exerkines for Aging and Metabolic Challenges

Published:2024-02-13 Issue:2 Volume:12 Page:57
ISSN:2075-4663
Container-title:Sports
language:en
Short-container-title:Sports

Author:

Saheli Mona¹,Moshrefi Mandana²,Baghalishahi Masoumeh¹,Mohkami Amirhossein³^ORCID,Firouzi Yaser⁴,Suzuki Katsuhiko⁵^ORCID,Khoramipour Kayvan⁶^ORCID

Affiliation:

1. Department of Anatomical Sciences, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, Iran

2. Department of Physiology and Pharmacology, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, Iran

3. Department of Exercise Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar 9617976487, Iran

4. Department of Exercise Physiology, Faculty of Sport Sciences, Shahid Bahonar University, Kerman 7616913439, Iran

5. Faculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan

6. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman 7619813159, Iran

Abstract

Addressing cognitive impairment (CI) represents a significant global challenge in health and social care. Evidence suggests that aging and metabolic disorders increase the risk of CI, yet promisingly, physical exercise has been identified as a potential ameliorative factor. Specifically, there is a growing understanding that exercise-induced cognitive improvement may be mediated by molecules known as exerkines. This review delves into the potential impact of aging and metabolic disorders on CI, elucidating the mechanisms through which various exerkines may bolster cognitive function in this context. Additionally, the discussion extends to the role of exerkines in facilitating stem cell mobilization, offering a potential avenue for improving cognitive impairment.

Funder

Neuroscience Research Center, Kerman University of Medical Sciences

Publisher

MDPI AG

Link

https://www.mdpi.com/2075-4663/12/2/57/pdf

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