Comparative Analysis of Hematological and Biochemical Changes in Neonates among Women with and without COVID-19 Infection during Pregnancy-Reference-Cited by-同舟云学术

Comparative Analysis of Hematological and Biochemical Changes in Neonates among Women with and without COVID-19 Infection during Pregnancy

Published:2023-08-10 Issue:8 Volume:10 Page:1370
ISSN:2227-9067
Container-title:Children
language:en
Short-container-title:Children

Author:

Popescu Daniela-Eugenia¹²^ORCID,Cerbu Simona³,Rosca Ioana⁴⁵,Lungu Nicoleta¹⁶,Trușculescu Ana Adriana⁷⁸^ORCID,Belengeanu Valerica⁹,Manea Aniko Maria¹,Dima Mirabela Adina¹,Gorun Florin¹⁰^ORCID,Popa Zoran Laurentiu¹,Crisan Doru Ciprian¹,Boia Marioara¹⁶

Affiliation:

1. Department of Obstetrics-Gynecology and Neonatology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania

2. Department of Neonatology, Premiere Hospital, Regina Maria Health Network, 300645 Timisoara, Romania

3. Discipline of Radiology and Medical Imaging, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania

4. Neonatology Department, Clinical Hospital of Obstetrics and Gynecology “Prof. Dr. P.Sirbu”, 060251 Bucharest, Romania

5. Faculty of Midwifery and Nursery, University of Medicine and Pharmacy “Carol Davila”, 020021 Bucharest, Romania

6. Department of Neonatology, “Louis Țurcanu” Children Emergency Clinical Hospital Timișoara, 300011 Timisoara, Romania

7. Pulmonology Department, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania

8. Center for Research and Innovation in Precision Medicine of Respiratory Diseases (CRIPMRD), “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania

9. Department of Genetics, Institute of Life Science, Faculty of Medicine, “Vasile Goldiş” Western University of Arad, 310025 Arad, Romania

10. Department of Obstetrics and Gynecology, Municipal Emergency Clinical Hospital Timisoara, 300172 Timisoara, Romania

Abstract

The aim of this study is to evaluate the test results of neonates delivered by COVID-19-positive mothers during pregnancy with those of neonates born to unvaccinated mothers who are COVID-19-free. A cohort study was conducted on 367 pregnant women who gave birth at Premiere Hospital, Timisoara, Romania, between May 2021 and February 2022. Two groups were established: Group 1, with 167 pregnant women infected with COVID-19, and Group 2, with 200 pregnant women who were not affected by COVID-19 during pregnancy. Maternal laboratory examination did not exhibit significant variations except for platelet count. In neonatal blood tests, WBC had a significantly lower median value in the group born to COVID-19-free mothers. Neonatal anemia and leukocytosis showed slightly higher prevalence in Group 1, but the differences were not statistically significant. This study suggests that maternal COVID-19 infection during pregnancy does not have significant associations with most maternal and neonatal characteristics.

Publisher

MDPI AG

Subject

Pediatrics, Perinatology and Child Health

Link

https://www.mdpi.com/2227-9067/10/8/1370/pdf

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