Effects of Sepsis on Immune Response, Microbiome and Oxidative Metabolism in Preterm Infants-Reference-Cited by-同舟云学术

Effects of Sepsis on Immune Response, Microbiome and Oxidative Metabolism in Preterm Infants

Published:2023-03-22 Issue:3 Volume:10 Page:602
ISSN:2227-9067
Container-title:Children
language:en
Short-container-title:Children

Author:

Parra-Llorca Anna¹²^ORCID,Pinilla-Gonzlez Alejandro¹²^ORCID,Torrejón-Rodríguez Laura¹²^ORCID,Lara-Cantón Inmaculada¹²^ORCID,Kuligowski Julia²^ORCID,Collado María Carmen³^ORCID,Gormaz María¹²,Aguar Marta¹²^ORCID,Vento Máximo¹²^ORCID,Serna Eva⁴^ORCID,Cernada María¹²

Affiliation:

1. Division of Neonatology, University and Polytechnic Hospital La Fe (HULAFE), 46026 Valencia, Spain

2. Neonatal Research Group, Health Research Institute La Fe (IISLAFE), 46026 Valencia, Spain

3. Department of Biotechnology, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), 46980 Valencia, Spain

4. Department of Physiology, University of Valencia, 46010 Valencia, Spain

Abstract

This is a narrative review about the mechanisms involved in bacterial sepsis in preterm infants, which is an illness with a high incidence, morbidity, and mortality. The role of the innate immune response and its relationship with oxidative stress in the pathogenesis are described as well as their potential implementation as early biomarkers. Moreover, we address the impact that all the mechanisms triggered by sepsis have on the dysbiosis and the changes on neonatal microbiota.

Publisher

MDPI AG

Subject

Pediatrics, Perinatology and Child Health

Link

https://www.mdpi.com/2227-9067/10/3/602/pdf

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