Affiliation:
1. Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21218, USA
Abstract
Down Syndrome is one of the most common chromosomal conditions in the world, affecting an estimated 1:400–1:500 births. It is a multisystem genetic disorder but has a wide range of ophthalmic findings. These include strabismus, amblyopia, accommodation defects, refractive error, eyelid abnormalities, nasolacrimal duct obstruction, nystagmus, keratoconus, cataracts, retinal abnormalities, optic nerve abnormalities, and glaucoma. These ophthalmic conditions are more prevalent in children with Down Syndrome than the general pediatric population, and without exception, early identification with thoughtful screening in this patient population can drastically improve prognosis and/or quality of life.
Subject
Pediatrics, Perinatology and Child Health
Reference70 articles.
1. Down syndrome: Current status, challenges and future perspectives;Kazemi;Int. J. Mol. Cell. Med.,2016
2. Ocular alignment, media, and eyelid disorders in Down syndrome;Makateb;Strabismus,2020
3. Ophthalmic manifestations of children with Down syndrome in Port Harcourt, Nigeria;Omobolanle;Clin. Ophthalmol.,2012
4. Ocular findings in Malaysian children with Down syndrome;Azlan;Singap. Med. J.,2006
5. Surveillance of vision and ocular disorders in children with Down syndrome;Stephen;Dev. Med. Child Neurol.,2007
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献