Updates in the Management of Congenital Melanocytic Nevi

Author:

Mologousis Mia A.123ORCID,Tsai Serena Yun-Chen34ORCID,Tissera Kristin A.35ORCID,Levin Yakir S.346ORCID,Hawryluk Elena B.234ORCID

Affiliation:

1. School of Medicine, Tufts University, Boston, MA 02111, USA

2. Dermatology Program, Boston Children’s Hospital, Boston, MA 02115, USA

3. Department of Dermatology, Massachusetts General Hospital, Boston, MA 02114, USA

4. School of Medicine, Harvard University, Boston, MA 02115, USA

5. School of Medicine, Duke University, Durham, NC 27710, USA

6. Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA

Abstract

Congenital melanocytic nevi (CMN) carry an increased risk of melanoma and may be disfiguring, and consensus regarding treatment recommendations is lacking. While clinical monitoring is the standard of care, many caregivers are interested in its removal to prevent psychosocial burden or to decrease risk. Although melanoma can occur regardless of CMN removal, there are a variety of treatments that may offer improved cosmesis or local symptom control, including surgical excision, laser therapy, and other superficially destructive techniques. Regardless of the selected management, these patients are monitored for ongoing melanoma risk. An extensive discussion with families regarding the risks and benefits of observation versus active intervention is essential. To facilitate these discussions, we herein summarize current CMN management strategies and considerations.

Funder

Pediatric Dermatology Research Alliance (PeDRA) Career Bridge funding

Publisher

MDPI AG

Subject

Pediatrics, Perinatology and Child Health

Reference127 articles.

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3. Congenital melanocytic nevi: Where are we now? Part I. Clinical presentation, epidemiology, pathogenesis, histology, malignant transformation, and neurocutaneous melanosis;Alikhan;J. Am. Acad. Dermatol.,2012

4. New recommendations for the categorization of cutaneous features of congenital melanocytic nevi;Krengel;J. Am. Acad. Dermatol.,2013

5. Neurocutaneous melanosis: Definition and review of the literature;Kadonaga;J. Am. Acad. Dermatol.,1991

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