Side Effects of Human Drug Use: An Overview of the Consequences of Eels’ Exposure to Cocaine

Author:

Rosati Luigi12ORCID,Caputo Ivana34ORCID,Lionetti Lillà34ORCID,Fontes Mayana Karoline56,Pereira Camilo Dias Seabra6ORCID,Capaldo Anna12ORCID

Affiliation:

1. Department of Biology, University of Naples Federico II, Via Cinthia Edifice 7, 80126 Naples, Italy

2. Center for Studies on Bioinspired Agro-Environmental Technology (BAT Center), 80055 Portici, Italy

3. Department of Chemistry and Biology “A. Zambelli”, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy

4. ELFID (European Laboratory for Food-Induced Diseases), University of Naples Federico II, via Pansini 5, 80131 Naples, Italy

5. Institute of Biosciences, Litoral Paulista Campus, São Paulo State University “Júlio de Mesquita Filho”, Praça Infante Dom Henrique s/n, São Vicente 11330-900, Brazil

6. Department of Marine Sciences, Federal University of São Paulo, Rua Maria Máximo 168, Santos 11030-100, Brazil

Abstract

The widespread use of drugs is a global problem which affects not only humans but also the environment around them, as research is showing the presence of these substances in different environmental matrices, like air, water, and soil. Above all, due to the remarkable pharmacological properties of drugs, it is discovered that organisms accidentally exposed to them, as aquatic organisms, undergo behavioral and physiological changes that can compromise their health, survival, and reproduction ability. In addition to this, we must consider the ability of some drugs to accumulate within these organisms, thus entering the food chain, and the possible interactions that drugs in water can establish with each other and with other possible pollutants, making the final effects on exposed organisms unpredictable. This article is an overview of the effects of one of these drugs, cocaine, one of the drugs commonly found in the aquatic environment, on European eel, an endangered species and known biomonitor of aquatic contamination.

Funder

University of Naples Federico II

São Paulo Research Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

MDPI AG

Subject

Ecology,Aquatic Science,Ecology, Evolution, Behavior and Systematics

Reference100 articles.

1. UNODC (2022). World Drug Report, UNODC. (United Nations Publication, sales, No. E.22.XI.8).

2. UNODC (2022). World Drug Report, UNODC. (United Nations Publication, sales, No. E.22.XI.8).

3. Illicit drugs and the environment—A review;Pal;Sci. Total Environ.,2013

4. Review on the occurrence and biological effects of illicit drugs in aquatic ecosystems;Fontes;Environ. Sci. Pollut. Res.,2020

5. Environmentally realistic concentrations of cocaine in seawater disturbed neuroendocrine parameters and energy status in the marine mussel Perna perna;Fontes;Comp. Biochem. Physiol. C,2022

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