Surgery or No Surgery? Exploring the Dilemma of Epistaxis Management in Patients with HHT

Author:

Passali Giulio Cesare123ORCID,Santantonio Mariaconsiglia34ORCID,Vecchioli Nadia23,Sollazzo Michela23,Rolesi Rolando23,Marotta Ilenia23,Corina Luigi23ORCID,Riccioni Maria Elena15,Gaetani Eleonora16,Galli Jacopo12

Affiliation:

1. Università Cattolica del Sacro Cuore, Largo F. Vito, 00168 Rome, Italy

2. Division of Otorhinolaryngology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy

3. Multidisciplinary Gemelli Group for HHT, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy

4. Ospedale Pediatrico Bambino Gesù, Via Torre di Palidoro s.n.c, 00054 Fiumicino, Italy

5. Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore School of Medicine, 00168 Rome, Italy

6. Department of Translational Medicine and Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy

Abstract

Background: Epistaxis, particularly in Hereditary Hemorrhagic Telangiectasia (HHT) patients, is a common otolaryngological emergency, often requiring complex management. A hierarchy of increasingly invasive interventions, from external compression of the nasal pyramid to nostril closure, is typically proposed and applied. Methods: We conducted a retrospective study on HHT patients to assess the effectiveness and longevity of invasive procedures postoperatively. Data were collected using the Epistaxis Severity Score (ESS) questionnaire. The primary focus was on changes in the frequency and intensity of epistaxis, while the secondary focus was on the overall quality of life. Results: This study found that invasive procedures initially improved the frequency and intensity of epistaxis in HHT patients. However, within 1 to 9 months postoperatively, these benefits often diminished, with hemorrhagic symptoms recurring at similar or worsened levels. Conclusions: The findings suggest a need for a cautious and restrained approach to using invasive treatments in managing epistaxis in HHT patients. Highly invasive procedures should be reserved for cases where less invasive methods fail, due to their temporary effectiveness and the risk of causing anatomical–functional changes in the rhino-sinus area, complicating future management of severe epistaxis.

Publisher

MDPI AG

Reference34 articles.

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