Prevention of Surgical Site Infections in Neonates and Children: Non-Pharmacological Measures of Prevention

Author:

Meoli AnielloORCID,Ciavola Lorenzo,Rahman Sofia,Masetti Marco,Toschetti Tommaso,Morini Riccardo,Dal Canto Giulia,Auriti Cinzia,Caminiti CaterinaORCID,Castagnola ElioORCID,Conti Giorgio,Donà Daniele,Galli LuisaORCID,La Grutta Stefania,Lancella Laura,Lima MarioORCID,Lo Vecchio AndreaORCID,Pelizzo Gloria,Petrosillo NicolaORCID,Simonini AlessandroORCID,Venturini ElisabettaORCID,Caramelli FabioORCID,Gargiulo Gaetano DomenicoORCID,Sesenna Enrico,Sgarzani RossellaORCID,Vicini Claudio,Zucchelli MinoORCID,Mosca Fabio,Staiano Annamaria,Principi NicolaORCID,Esposito Susanna,

Abstract

A surgical site infection (SSI) is an infection that occurs in the incision created by an invasive surgical procedure. Although most infections are treatable with antibiotics, SSIs remain a significant cause of morbidity and mortality after surgery and have a significant economic impact on health systems. Preventive measures are essential to decrease the incidence of SSIs and antibiotic abuse, but data in the literature regarding risk factors for SSIs in the pediatric age group are scarce, and current guidelines for the prevention of the risk of developing SSIs are mainly focused on the adult population. This document describes the current knowledge on risk factors for SSIs in neonates and children undergoing surgery and has the purpose of providing guidance to health care professionals for the prevention of SSIs in this population. Our aim is to consider the possible non-pharmacological measures that can be adopted to prevent SSIs. To our knowledge, this is the first study to provide recommendations based on a careful review of the available scientific evidence for the non-pharmacological prevention of SSIs in neonates and children. The specific scenarios developed are intended to guide the healthcare professional in practice to ensure standardized management of the neonatal and pediatric patients, decrease the incidence of SSIs and reduce antibiotic abuse.

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Microbiology (medical),General Pharmacology, Toxicology and Pharmaceutics,Biochemistry,Microbiology

Reference158 articles.

1. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

2. Strategies to Prevent Surgical Site Infections in Acute Care Hospitals: 2014 Update

3. Global Guidelines for the Prevention of Surgical Site Infection;World Health Organization,2018

4. Surgical site infection (SSI) Event;National Healthcare Safety Network, Centers for Disease Control and Prevention,2022

5. Surgical Site Infections: Prevention and Treatment. NICE 2019 [Update 2020]. Clinical Guideline NG 125 https://www.nice.org.uk/guidance/ng125

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