Abstract
The authors aim to present a narrative review of research on the inflammatory aetiology of depression. Depression is a psychiatric disorder, constituting the most common reason of disability due to a health condition. It has been estimated that at least one in six people suffer from depression at some point of their lives. The aetiology of depression, although researched extensively all around the world, still remains unclear. Authors discuss the possible role of inflammation in depression, the neurodevelopmental theory of depression as well as associations between cognition and depression. Possible associations between memory dysfunction among depressive patients and inflammatory markers are included. The associations between the immune system, depression and cognition are observed. Possible mediating factors between these areas include personality traits, hormonal imbalance and functioning of the brain areas. The question as to what mediating factors are involved is still open to research.
Reference103 articles.
1. Depression and Other Common Mental Disorders Global Health Estimates
www.who.int
2. The Global Burden of Disease Harvard Medical School;Murray,1996
3. Global regional and national incidence, prevalnce and years lived with disability for 310 diseases and injuries, 1990–2015, a systematic analysis for the Global Burden of Disease Study;Lancet,2015
4. Global variation in the prevalence and incidence of major depressive disorder: a systematic review of the epidemiological literature
5. The prevalence of common mental disorders in the population of adult Poles by sex and age structure – an EZOP Poland study
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